Hepatosplenic candidiasis--a contraindication to marrow transplantation?
نویسندگان
چکیده
منابع مشابه
Hepatosplenic candidiasis--a contraindication to marrow transplantation?
To determine whether a prior history of hepatosplenic candidiasis resulted in increased Candida-associated morbidity and mortality after marrow transplant, 15 consecutive patients with biopsy-proven hepatosplenic candidiasis were observed prospectively. All patients received amphotericin B before transplant. Amphotericin B was continued at a dose of 0.5 mg/kg/day from conditioning through marro...
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Regular preoperative application of corticosteroids has been considered as a contraindication to lung transplantation for fear of an increased risk of postoperative morbidity and mortality. Recently, however, we have accepted patients for transplantation in whom treatment with steroid medication could not be terminated preoperatively. Up to February 1991, 27 unilateral and bilateral transplanta...
متن کاملPrevious occurrence of life-threatening abdominal infection is not a contraindication to bone marrow transplantation.
Sir, Protracted severe infections during the post-induction aplastic phase in leukemic patients may cause delay and/or modification of the planned treatment strategy;1 in particular, patients may be considered no longer eligible for bone marrow transplantation (BMT) owing to a high risk of suffering infection reactivation.2,3 We report on seven patients admitted to our Unit because of acute mye...
متن کاملHepatosplenic candidiasis: successful treatment with fluconazole.
PURPOSE To determine if fluconazole is effective treatment for hepatosplenic candidiasis that has not resolved with amphotericin B and flucytosine treatment. PATIENTS AND METHODS Six patients (ages 3 to 44) with acute leukemia and hepatosplenic candidiasis who did not respond to prior antifungal therapy were treated with fluconazole. RESULTS All six patients had fever and three had nausea a...
متن کاملHepatosplenic candidiasis in patients with acute leukaemia.
A retrospective study of 23 patients with acute leukaemia and hepatosplenic candidiasis (HSC) was conducted to evaluate clinical treatment characteristics in terms of amount and duration of antifungal agents and to assess treatment outcome. Patients were admitted to two major tertiary care centres between 1990 and 1998. The diagnosis of HSC was based on clinical, blood cultures, histologic and ...
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ژورنال
عنوان ژورنال: Blood
سال: 1994
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v84.8.2811.2811